A storm that dropped snow in the Midwest spread across the Tennessee and Ohio Valleys, bringing more misery to some places just starting to clean up from deadly weekend floods.
Up to 10 inches of snow was possible through Thursday night along the Atlantic Coast in Virginia and significant ice accumulations were forecast in eastern North Carolina, the National Weather Service said.
Virginia State Police reported 53 accidents by late Wednesday morning. Accidents also closed portions of Interstate 95 and I-85 near Raleigh, North Carolina.
Nearly 4,000 flights were canceled or delayed across the U.S., including more than 300 in and out of Charlotte Douglas International Airport in North Carolina, according to the flight-tracking site Flightaware.com.
Elsewhere, a polar vortex sent temperatures plunging from Montana to southern Texas. The biggest batch of record cold temperatures are expected early Thursday and Friday, said weather service meteorologist Andrew Orrison.