His nomination now will face a full Senate vote, despite concerns about the work he's done to sow doubts around vaccine safety and his potential to profit off lawsuits over drugmakers.
To gain control of the $1.7 trillion Health and Human Services agency, Kennedy will need support from all but three Republicans if Democrats uniformly oppose him.
Republican Sen. Bill Cassidy of Louisiana, who is also a physician and sits on the finance committee, voted to advance Kennedy's confirmation. Last week, during Kennedy's hearings, Cassidy repeatedly implored Kennedy to reject a disproven theory that vaccines cause autism, to no avail. He ended the hearing by saying he was "struggling" with the vote.
Republican Sens. Susan Collins of Maine, Lisa Murkowski of Alaska and Mitch McConnell of Kentucky are all seen as potential no votes, too, because they voted against President Donald Trump's defense secretary nominee and have expressed concerns about Kennedy's anti-vaccine work.
In a CBS "60 Minutes" interview that aired Sunday, McConnell declined to say how he would vote on Kennedy's nomination but reiterated "vaccines are critically important."
Democrats, meanwhile, continue to raise alarms about Kennedy's potential to financially benefit from changing vaccine guidelines or weakening federal lawsuit protections against vaccine makers if confirmed as health secretary.
Kennedy said he'll give his son all of the referral fees in legal cases against vaccine makers, including the fees he gets from referring clients in a case against Merck. Kennedy told the committee he's referred hundreds of clients to a law firm that's suing Merck's Gardasil, the human papillomavirus vaccine that prevents cervical cancer. He's earned $2.5 million from the deal over the past three years.
As secretary, Kennedy will oversee vaccine recommendations and public health campaigns for the $1.7 trillion agency, which is also responsible for food and hospital inspections, providing health insurance for millions of Americans and researching deadly diseases.